TABLE 1.
The overall results of all polymorphisms of the G72/G30 genes
| Markers | OR (95% C.I.) | P(Z) | P(Q) |
|---|---|---|---|
| M12 (A/G)a (8)b | 1.12 (1.02, 1.24) | 0.0225 | 0.0031 |
| M13 (A/C) (4) | 1.06 (0.9, 1.24) | 0.4794 | 0.3857 |
| M14 (A/G) (8) | 0.99 (0.89, 1.1) | 0.8909 | 0.1388 |
| M15 (A/G) (8) | 1.15 (1.04, 1.27) | 0.0086 | 0.0030 |
| M16 (A/G) (3) | 1.12 (0.92, 1.35) | 0.2521 | 0.7874 |
| M18 (A/C) (3) | 0.95 (0.79, 1.13) | 0.5571 | 0.5008 |
| M19 (A/G) (4) | 0.98 (0.83, 1.16) | 0.8451 | 0.2428 |
| M20 (A/G) (3) | 1.03 (0.86, 1.23) | 0.7663 | 0.7641 |
| M21 (C/T) (4) | 1.14 (0.97, 1.34) | 0.1090 | 0.7115 |
| M22 (A/G) (7) | 1.04 (0.93, 1.17) | 0.5096 | 0.0151 |
| M23 (C/T) (7) | 0.88 (0.79, 0.97) | 0.0136 | 0.0004 |
| M24 (A/T) (4) | 0.8 (0.69, 0.91) | 0.0010 | 0.6421 |
| rs1935062 (A/C) (4) | 0.91 (0.79, 1.04) | 0.1611 | 0.3605 |
P(Z), Z-test used to determine the significance of the overall OR. P-values < 0.05 are in italics. P(Q), the Cochran's χ2-based Q-statistic test was used to assess the heterogeneity. P(T), T-test was used to evaluate the significance of publication bias. No P(T) < 0.05 (not shown). The NCBI rs ID for the M-SNPs (Chumakov et al. 2002) are the following: M12 (rs3916965), M13 (rs3916966), M14 (rs3916967), M15 (rs2391191), M16 (rs3918341), M18 (rs947267), M19 (rs778294), M20 (rs3916970), M21 (rs3916971), M22 (rs778293), M23 (rs3918342), and M24 (rs1421292).
a
The first allele is the risk allele.
b
The number of studies included are indicated in parentheses.