TABLE 2.
Genes in the L5Jcs1 critical region
| Gene | Exons | KO | Sequenced |
|---|---|---|---|
| C1qtnf7 (C1q and TNF-related protein 7) | 6 | Yes | |
| 5730509K17Rik | 40 | ||
| Fbxl5 (F-box and leucine-rich-repeat protein 5) | 9 | Yes | |
| Bst1 (bone marrow stromal antigen 1) | 9 | Yesc | |
| Cd38 | 8 | Yesa | |
| Ppih (peptidyl prolyl isomerase H) | 1 | ||
| Fgfbp1 (fibroblast growth factor binding protein 1) | 2 | Yes | |
| Prom1 (prominin 1) | 27 | ||
| 4932414K18Rik (Tapt1) | 14 | Yes | |
| Ldb2 (LIM homeodomain binding 2) | 9 | Yesb |
C1qtnf7 is subject to alternative splicing; all isoforms were sequenced. Primers used for sequencing are in supplemental Table 1 at http://www.genetics.org/supplemental/. KO, knockout allele available.
a
Mutants are viable.
b
A Lexicon viable mutant.
c
All coding regions but exon 5 were sequenced.