TABLE 1.
Echocardiographic analysis of wild-type and 14-3-3τ+/− micea
| Genotype (nb) | HR (min−1) | LVIDd (mm) | (LVIDs) (mm) | LVPWd (mm) | IVSd (mm) | LVM (mg) | BW (g) | FS (%) |
|---|---|---|---|---|---|---|---|---|
| Wild type (6) | 665 ± 46 | 3.2 ± 0.22 | 1.32 ± 0.12 | 0.60 ± 0.07 | 0.67 ± 0.07 | 58.2 ± 6.8 | 22.2 ± 1.1 | 58.4 ± 2.7 |
| 14-3-3τ+/− (6) | 660 ± 11 | 3.2 ± 0.15 | 1.12 ± 0.17 | 0.57 ± 0.10 | 0.67 ± 0.05 | 56.0 ± 8.5 | 21.2 ± 1.5 | 64.8 ± 5.5 |
a
Twelve-week-old awake mice underwent transthoracic echocardiography. HR, heart rate; LVIDd, left ventricular internal dimension in diastole; LVIDs, left ventricular internal dimension in systole; LVPWd, left ventricular posterior wall thickness in diastole; IVSd, interventricular septal thickness in diastole; LVM, calculated left ventricular mass; BW, body weight; FS, fractional shortening.
b
n, number of mice studied.