TABLE 3.

Echocardiographic analysis of wild-type and 14-3-3τ^+/− mice after myocardial infarction^a,b

Genotype (nc)	SWMSI (1 day)	EDV (7 days) (mm3)	EDVI (7 days) (mg)	ESV (7 days) (mm3)	EF (7 days)
Wild type (12)	1.40 ± 0.03	70.7 ± 7.2	3.05 ± 0.41	47.3 ± 7.7	38.1 ± 5.4
14-3-3τ+/− (11)	1.37 ± 0.03	105.1 ± 12.3	3.80 ± 0.40	78.9 ± 11.7	28.3 ± 3.2

^aTwelve-week-old awake mice underwent transthoracic echocardiography 1 or 7 days after experimental myocardial infarction by ligation of the left coronary artery. SWMSI, segmental wall motion score index (an SWMSI value of 1 indicates normal wall thickening, whereas an SWMSI score of 2 indicates cardiac akinesis). EDV, end diastolic volume; EDVI, end diastolic volume index (end diastolic volume/body weight in mg); ESV, end systolic volume (mm³); EF, ejection fraction.

^bP values were as follows: for SWMSI, 0.37; for EDV, 0.022; for EDVI, 0.20; for ESV, 0.03; for EF, 0.14.

^cn, number of mice studied.