TABLE 2.

Genotypes of progeny from Sulf2^+/− parents

Strain and generationa	% 129P2	No. of mice in litter/total no. of mice	No. of mice with indicated genotype			P valueb
			+/+	+/−	−/−
C57BL/6
N2 Obs	25.0	20/152	52	73	27	0.015*
N2 Exp			38	76	38
N3 Obs	12.5	31/191	49	102	40	0.420
N3 Exp			47.75	95.5	47.75
N7 Obs	0.8	16/109	29	51	29	0.800
N7 Exp			27.25	54.5	27.25
FVB/N
N1 Obs	12.5	10/90	22	45	23	1.000
N1 Exp			22.5	45	22.5
N7 Obs	0.2	9/61	16	28	17	0.801
N7 Exp			15.25	30.5	15.25

^aN indicates the number of successive backcrosses needed to generate parental Sulf2^+/−. Obs, observed; Exp, expected.

^bProbability of a non-Mendelian outcome determined by a χ² test. *, P < 0.05.