Table 2.
Age (weeks) | Genotype | Testis Weight (mg) | SV weight (mg) | Testicular Testosterone (ng/g testis) | Serum Testosterone (ng/ml) | LH (ng/ml) | FSH (ng/ml) |
---|---|---|---|---|---|---|---|
3 | WT | 54.2±4.1 | 3.1±0.4 | 1.5±0.4 | 0.22±0.02 | 0.50±0.18 | 19.1±2.0 |
YHR+ | 35.1±1.7* | 5.8±0.6* | 18±2.9* | 0.76±0.47* | 0.1±0 *a | 1.0±0.1* | |
5 | WT | 120.0±7.9 | 16.4±3.0 | 4.8±0.9 | 0.37±0.09 | 0.41±0.22 | 33.5±3.3 |
YHR+ | 65.2±2.2* | 31.1±5.1* | 69.9±5.1* | 1.35±0.12* | 0.13±0.02* | 2.8±0.2* | |
8 | WT | 177.9±4.0 | 113.3±5.3 | 100.8±49.1 | 7.0±2.5 | 0.26±0.03 | 38.7±2.3 |
YHR+ | 106.7±4.0* | 99.0±10.8 | 72.6±11.9 | 1.7±0.5 | 0.35±0.05 | 16.6±3.8* | |
12 | WT | 200.1±2.4 | 191.6±10.2 | 78.1±50.5 | 0.87±0.27 | 0.91±0.50 | 42.6±3.1 |
YHR+ | 156.1±3.7* | 143.5±5.6* | 102.3±47.5 | 3.8±1.9 | 0.26±0.03 | 19.6±1.5* |
Data are mean ±SEM (n=5–10)
significantly different from WT controls, P<0.05
values were below the standard curve and were assigned the value of the lowest standard (0.1 ng/ml).