Table 3.

Receptor Density After 60 Days of Withdrawal – Mean (+SEM) density (fmol/mg) of D1, D2, and NMDA receptors in the VTA, N.Acc Shell, N.Acc Core, Dorsal Striatum, and mPFC in the Sal, Coc1h, and Coc6h groups 60 days after the last self-administration session.

	Saline	Coc1h	Coc6h
D1
mPFC	15 ± 2	18 ± 2	12 ± 2
N.Acc Core	37 ± 4	42 ± 3	42 ± 3
N.Acc Shell	27 ± 6	27 ± 3	31 ± 6
Striatum	62 ± 6	65 ± 3	72 ± 5
VTA	4 ± 1	6 ± 1	5 ± 1
D2
mPFC	242 ± 15	253 ± 24	261 ± 23
N.Acc Core	242 ± 25	242 ± 25	251 ± 8
N.Acc Shell	278 ± 30	220 ± 17 *	297 ± 18
Striatum	173 ± 23	184 ± 14	175 ± 20
VTA	207 ± 17	193 ± 31	190 ± 23
NMDA
mPFC	357 ± 37	298 ± 49	311 ± 37
N.Acc Core	217 ± 22	229 ± 32	227 ± 31
N.Acc Shell	190 ± 28	205 ± 27	190 ± 27
Striatum	246 ± 19	206 ± 27	255 ± 23
VTA	70 ± 9	107 ± 14	73 ± 15

^*Significantly different than Coc6h