Table 1.
Echocardiographic parameters in 16 healthy dogs before (M0) and during anesthesia (M1, M2, M3) with isoflurane (1.0 MAC) (mean values, s)
| M0 Baseline | M1 25 minutes | M2 40 minutes | M3 55 minutes | P ANOVA | |
|---|---|---|---|---|---|
| HR (bpm) | 98.91, s = 23.56 | 113.81, s = 17.45 | 110.75, s = 11.51 | 112.75, s = 13.81 | 0.0632 |
| PEP (msec) | 50.31, s = 15.90 | 74.00, s = 21.27a | 72.43, s = 14.90a | 73.93, s = 16.56a | 0.0003 |
| LVET (msec) | 216.00, s = 21.68 | 217.43, s = 26.07 | 218.81, s = 30.14 | 221.56, s = 21.15 | 0.9335 |
| PEP/LVET | 0.23, s = 0.08 | 0.34, s = 0.10a | 0.33, s = 0.06a | 0.33, s = 0.06a | 0.0010 |
| IVRT (msec) | 42.81, s = 13.01 | 66.81, s = 13.65a | 69.31, s = 15.67a | 76.06, s = 21.26a | < 0.0001 |
| Tei-index | 0.43, s = 0.10 | 0.65, s = 0.11a | 0.65, s = 0.09a | 0.67, s = 0.11a | < 0.0001 |
HR — heart rate; PEP — e-ejection period; LVET — left ventricular ejection time; PEP/LVET — PEP-to-LVET ratio; IVRT — isovolumic relaxation time; ANOVA — analysis of variance; s — standard deviation; bpm — beat per minute; msec — millisecond
a
Statistically different from baseline (P < 0.05)
MAC — mean alveolar concentration