Table I. Potential Benefits and Harms of Genetic Testing of Children.

Category	Benefits	Harms
Mecical issues ..................	Early and effective preventive or therapeutic interventions Increased surveillance Avoiding unnecessary surveillance Refinement of prongosis Clarification of diagnosis	Ineffective or harmful preventive or therapeutic interventions
Psychosocial issues .........	Reduction of uncertainty Reduction of anxiety Opportunity for psychological adjustment Ability to make realistic plans for education, employment, insurance, and personal relationships Alerting other family members to genetic risk	Alteration of self image Distortion of parents' perception of child Increased anxiety and guilt Altered expectations by self or others for education, employment, and personal relationships Identifying other family members with late-onset diseases Discrimination in employment and in obtaining insurance Detection of misattributed paternity or adoption
Reproductive issues ........	Avoiding birth of child with genetic disease Preparing for birth of child with genetic disease Informed family-planning decisions by parents	Coerced decisions