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. 2005 Dec;116(4):541–552. doi: 10.1111/j.1365-2567.2005.02259.x

Figure 3.

Figure 3

Monocytes down-regulated activation molecules on natural killer (NK) cells from patients with advanced tuberculosis (A-TB). Peripheral blood mononuclear cells (PBMC) (grey bar) and monocyte-depleted mononuclear cells (grey black bar) from 10 patients with moderate tuberculosis (M-TB), 13 patients with advanced tuberculosis (A-TB) and eight healthy controls (N) were incubated in complete medium (control), Mycobacterium tuberculosis or M. tuberculosis plus interleukin (IL)-15 or IL-18 for 24 hr. The expression of CD16, CD69 and CD11a molecules on CD3 CD56+ cells was then determined by flow cytometry. Results are expressed as mean fluorescence intensity (MFI) for CD16 and CD11a molecules and percentage of CD69+ cells [mean ± standard error of the mean (SEM)]. Statistical differences: monocyte-depleted versus PBMC: *P < 0·05; **P < 0·01.