Table 6.
% IFN-γ+ NK cells | ||
---|---|---|
PBMC from | Control PBMC | M.tb-stimulated PBMC |
M-TB (n = 5) | 1·0 ± 0·5 | 5·8 ± 0·8* |
A-TB (n = 5) | 0·4 ± 0·3 | 2·5 ± 0·9 |
N (n = 5) | 0·6 ± 0·3 | 7·5 ± 0·7* |
Peripheral blood mononuclear cells (PBMC) from patients with moderate tuberculosis (M-TB) and advanced tuberculosis (A-TB) and healthy controls (N) were incubated in complete medium (control) or with M. tuberculosis (M.tb) for 24 hr and then the percentage of IFN-γ+ cells on CD3– CD56+ cells was evaluated by flow cytometry. Results are expressed as mean ± standard error of the mean (SEM). Statistical differences: control versus M. tuberculosis-stimulated PBMC:
P < 0·05.