Table 1.
Genesa | Function |
Aadc, Ant2 (Slc25a5), Calb1, Dat (Slc6a3), Girk2 (Kcnj6), Igf1, Ptx3, Th | Markers of dopaminergic neurons |
En1, En2, Lmx1bb, Pax5, Shh, Wnt1 | Markers of dopaminergic progenitors |
Adh2, Lhx1 (Lim1), Lhx5 (Lim2) | Markers of dopaminergic progenitors maturation |
Drd2b, Vmat2 | Markers of mature dopaminergic neurons |
Gfra1, Gfra2, Gfra3, Gfra4, Otx2 | Markers of early dopaminergic neurons |
Dlx1, Dlx2, Flj38973, Lmx1a | Related to differentiation of dopaminergic neurons |
Adcy7, Alcam, Art (Artn), Bcl11a, Calca, Cart, Cbln1, Cdh2, Col11a1, Cx43, D1lip (Drd1ip), Darpp32 (Ppp1r1b), Dbh, Doc2a, Drd1, Drd3, Drd4, Drd5, Drip78 (Dnajc14), Egln3 (Phd3), Egr1, Fos, Fxyd6, Galm, Ghr, Grin2c, Grp, Gsbs (C7orf16), Hs6st2, Igfbp4, Kcna5, Kcnab1, Math2, Mlp (Marcksl1), Moxd1, Mpp3, Nrip3, Nrp2, Nt (Nts), Ntn (Nrtn), Nurr1 (Nr4a2), Pac1 (Adcyap1r1), Pacap, Plagl1 (Zac), Pvrl3 (Nectin 3), Rab3c, Rcn1, Slc17a6 (Vglut2), Slc6a1, Sox6, Spp1, Tacr3, Trhr, Zfp161, Vav3, Zdhhc2 | Related to dopaminergic system |
The majority of genes listed may also possess other functions, not related to dopaminergic system. Four entries were omitted from the table, representing candidate markers of dopaminergic system now undergoing characterization (unpublished data).
a Italics indicates genes up-regulated (Log2 ratio >1.0) in dopaminergic differentiation experiment. Rcn1, Log2 ratio >0.97; Fxyd6 and Zfp161, Log2 ratio >0.7).
b May also possess other functions related to dopaminergic system.