Skip to main content
. 2007 Feb 8;8:46. doi: 10.1186/1471-2164-8-46

Table 2.

Selected categories of NeuroStem chip entries.

Category Functional role Examples
I. Stemness Recognized markers of stemness Oct3/4, Nanog, Tdgf1
Candidate markers of stemness Cpxm1, Hook1, Ddx21
Germ cell markers Rif1, Bnc1, Bnc2
Hematopoietic stem cell markers Hoxb4, Cdcp1, C1qr1
Mesenchymal stem cell marker Bmpr1a, Bmpr2, Cd49a
II. Proliferation Proliferation markers Ki67, Pcna, Myc
Neural proliferation markers Emx1, Gbx2
III. Development Differentiation Lifr, Ebaf, Lyar
 Neuronal differentiation Ren, Rai1, Neurod2
  Dopaminergic differentiation Dlx1, Dlx2, Lmx1a
Neuronal maturation Mecp2, Ebf3, Sox4
Neuronal process formation Hmgb1, Rage
Axonal elongation and branching Pi3, Map1b, Slit1
IV. Neural markers Pan-neural markers Gap43, Nfh, Eno2
Markers of dopaminergic neurons Th, Aadc, Dat
Markers of cholinergic neurons Ngf
Markers of spinal neurons Hoxc6
Glial markers S100β, Cd68
 Astrocyte markers Gfap, Tapa1
 Oligodendrocyte markers Mag, Mobp, Omg
V. Distinct markers Normal tissues
 Liver Gata6, G6pd, Fabp1
 Pancreas Tff3, Sst, Pax4
 Skeletal muscle Itga7, Dmd, Tnnt3
 Cardiac muscle Nkx2.5, Anf, Myhca
 Smooth muscle Actg2, Cnn1, Sm22α
 Endothelial cells Flt1, Vwf, Pecam1
Blood cell subtypes Cd4, Cd8, Cd19
Cancer cells Maspin
 Pancreatic cancer Kras2
 Colon cancer Mina53
 Breast cancer Klk7
 Prostatic cancer Hpn, Mat8
 Lung cancer Rab5a, Tp63
 Ovarian cancer Mgb2
 Hodgkin's lymphoma Ptp4a, Atf5, p21snft
VI. Relevant groups Apoptosis-related p53, Psip1, Birc2
Telomere-related Tert, Terf2, Rap1
Antioxidants Sod1, Sod2, Gpx1
Imprinted genes Tseb3, Gnas1, Grb10
FZD group Fzd1, Fzd3, Sfrp1
WNT group Wnt1, Wnt7a, Wisp1
BMP group Bmp1, Bmp2, Bambi
STAT group Stat1, Stat3, Pias1
FGF group Fgf1, Fgf2, Fgfr4
GDF group Gdf2, Gdf3, Gdf9
Caspases group Casp1, Casp2, Hsp70
Cyclins group Ccna1, Ccnc, Cdk1
Kruppel-like group Klf2, Klf9, Znf184

Due to functional redundancy, individual genes may fit into more than one category.