Table 4.
Top 25 genes up-regulated in hESC population, as compared to human universal reference RNA.
| N | Gene indexa | Gene name | Log2 Ratio | S.E.M (%) | Spot Error |
| 1. | Hesx1 | Homeo box expressed in ES cells 1 | 4.11 | 5.76 | 0.0575 |
| 2. | Grem1 | Gremlin 1 homolog, cysteine knot superfamily | 3.86 | 7.14 | 0.1012 |
| 3. | Cdh6 | Cadherin 6 (K-cadherin) | 3.49 | 3.88 | 0.0186 |
| 4. | Gja1 | Gap junction protein, α1 (connexin 43) | 3.49 | 7.10 | 0.0485 |
| 5. | Htr2b | 5-hydroxytryptamine (serotonin) receptor 2B | 3.45 | 8.91 | 0.0655 |
| 6. | Emx2 | Empty spiracles homolog 2 (Drosophila) | 3.24 | 6.10 | 0.1202 |
| 7. | Epo | Erythropoietin | 3.22 | 9.67 | 0.0407 |
| 8. | Fzd7 | Frizzled homolog 7 (Drosophila) | 3.08 | 4.99 | 0.0317 |
| 9. | Kal1 | Kallmann syndrome 1 sequence | 3.05 | 3.10 | 0.0684 |
| 10. | Auts2 | Autism susceptibility candidate 2 | 3.03 | 7.49 | 0.0088 |
| 11. | Zic3 | Zic family member 3 heterotaxy 1 | 2.98 | 5.59 | 0.0709 |
| 12. | Rds | Retinal degeneration, slow | 2.95 | 10.00 | 0.0756 |
| 13. | Ddit4l | DNA-damage-inducible transcript 4-like | 2.90 | 4.90 | 0.0357 |
| 14. | Crispld1 | Cysteine-rich secretory protein LCCL domain containing 1 (LOC83690) | 2.87 | 5.04 | 0.0990 |
| 15. | Lrrn1 | Leucine rich repeat neuronal 1 | 2.74 | 3.94 | 0.1002 |
| 16. | Gpr23 | G protein-coupled receptor 23 | 2.74 | 6.02 | 0.0702 |
| 17. | Mgc16186 | Hypothetical protein MGC16186 | 2.70 | 3.50 | 0.1592 |
| 18. | Par1 | Prader-Willi/Angelman region-1 | 2.69 | 18.44 | 0.0953 |
| 19. | Nap1l3 | Nucleosome assembly protein 1-like 3 | 2.69 | 4.00 | 0.0398 |
| 20. | Cecr2 | Cat eye syndrome critical region protein 2 | 2.65 | 6.40 | 0.0082 |
| 21. | Fgfr2 | Fibroblast growth factor receptor 2 | 2.64 | 5.11 | 0.0545 |
| 22. | Klkb1 | Kallikrein B, plasma (Fletcher factor) 1 | 2.63 | 9.96 | 0.0255 |
| 23. | Calb1 | Calbindin 1, 28kDa | 2.61 | 1.45 | 0.0719 |
| 24. | Fbn3 | Fibrillin 3 | 2.60 | 12.68 | 0.0462 |
| 25. | Id4 | Inhibitor of DNA binding 4 | 2.50 | 6.44 | 0.0467 |
Only entries with spot intensity in hESC sample >100 are shown. Entries are sorted based on average Log2 ratio (after filtering for expression in all 4 technical replicates). S.E.M., standard error of the mean expressed as percentage of the mean; Spot Error, estimate of the average measurement error for all spots for the given reporter across the 4 technical replicates.
a Italics indicates genes down-regulated (Log2 ratio < -1.0) in dopaminergic differentiation experiment.