Table 5.
Embryonic stem cell marker genes expressed in hES SA02 cell line, as detected by the NeuroStem Chip analysis
| N | Gene indexa | Gene name | Log2 Ratio | S.E.M (%) |
| 1. | Hesx1 | Homeo box expressed in ES cells 1 | 4.11 | 5.76 |
| 2. | Grem1 | Gremlin 1 homolog, cysteine knot superfamily | 3.86 | 7.14 |
| 3. | Gja1 | Gap junction protein, α1 (connexin 43) | 3.49 | 7.10 |
| 4. | Zic3 | Zic family member 3 heterotaxy 1 | 2.98 | 5.59 |
| 5. | Dnmt3b | DNA (cytosine-5)-methyltransferase 3β | 2.26 | 6.25 |
| 6. | Sfrp1 | Secreted frizzled-related protein 1 | 2.01 | 8.80 |
| 7. | Kiaa1573 | KIAA1573 protein | 1.98 | 2.48 |
| 8. | Dppa4 | Developmental pluripotency associated 4 | 1.97 | 2.80 |
| 9. | Sox2 | SRY (sex determining region Y)-box 2 | 1.86 | 12.44 |
| 10. | Foxo1a | Forkhead box O1A (rhabdomyosarcoma) | 1.85 | 9.15 |
| 11. | Hmgb1 | High-mobility group box 1 | 1.84 | 1.71 |
| 12. | Ctbp2 | C-terminal binding protein 2 | 1.77 | 9.16 |
| 13. | Lin28 | Lin-28 homolog (C. elegans) | 1.52 | 20.32 |
| 14. | Utf1 | Undifferentiated embryonic cell transcription factor | 1.21 | 9.28 |
| 15. | Lefty1 | Left-right determination factor 1 | 1.06 | 8.72 |
Only entries with spot intensity in hESC sample >100 and Log2 ratio >1 are shown. Entries are sorted based on average Log2 ratio (after filtering for expression in all 4 technical replicates). S.E.M., standard error of the mean expressed as percentage of the mean.
a Italics indicates genes down-regulated (< -1.0 Log2 ratio) in dopaminergic differentiation experiment. Nanog is down-regulated with Log2 ratio < -0.6.