Figure 7. Mutants in the SREBP Pathway, but Not the tco1Δ Mutant, Display Hypersensitivity to Fluconazole.

Cells (10⁴ cells/ml) of wild-type and each mutant strain were cultured in YNB for three d in 96-well format in the presence of 0.0045–30 μg/ml fluconazole, after which relative growth was assessed using OD₆₀₀ measurements. Data shown are an average of at least three independent cultures for each strain. Error bars represent standard deviations.