TABLE 1.
MIC distributions of oxazolidinones for linezolid-susceptible isolates
| Organism (no. of isolates) | Antimicrobial | No. of isolates with MIC (μg/ml) of:a
|
|||||
|---|---|---|---|---|---|---|---|
| 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | ||
| MRSA (47) | RWJ-416457 | 1 | 4 | 17 | 25 | ||
| Linezolid | 1 | 10 | 22 | 14 | |||
| MSSA (56) | RWJ-416457 | 1 | 21 | 34 | |||
| Linezolid | 1 | 0 | 35 | 20 | |||
| Methicillin-resistant | RWJ-416457 | 1 | 17 | 35 | 1 | ||
| coagulase-negative | Linezolid | 1 | 2 | 22 | 26 | ||
| staphylococci (51) | |||||||
| Methicillin-susceptible | RWJ-416457 | 17 | 39 | ||||
| coagulase-negative | Linezolid | 1 | 34 | 21 | |||
| staphylococci (56) | |||||||
| E. faecalis (49) | RWJ-416457 | 31 | 18 | ||||
| Linezolid | 48 | 1 | |||||
| E. faecium (49) | RWJ-416457 | 19 | 30 | ||||
| Linezolid | 44 | 5 | |||||
a
Modal values are shown in bold font.