TABLE 1.

In vitro activities of reserpine, omeprazole, and the pyrrolo[1,2-a]quinoxaline derivatives 1a to 1k as EPIs by the disk diffusion method for SA-1199B^a

Strain	EPI	EPI concn (μg/ml)	Inhibition zone diameter (mm)
			Nor	Cip	Ofx	Lvx	Spx	Mxf	C
SA-1199			27	26	27	30	30	31	27
SA-1199B			6	13	18	21	27	27	24
	Res	128	13	22	21	24	28	28	25
		64	12	20	20	24	27	28	25
		32	12	18	19	24	27	28	24
		16	9	16	19	22	27	28	24
	Om	128	14	22	23	25	28	30	25
		64	12	19	20	23	27	29	24
		32	6	15	18	21	27	27	24
		16	6	13	18	21	26	27	24
	1a	128	10	19	23	24	28	28	25
	1b	128	13	22	25	24	28	28	26
	1c	128	15	24	25	24	27	28	26
	1d	128	16	24	25	24	29	28	27
	1e	128	18	25	26	27	28	28	27
	1f	128	10	19	21	23	27	27	25
	1g	128	6	15	20	23	27	27	25
	1h	128	6	15	19	22	27	27	25
	1i	128	6	14	19	22	27	27	25
	1j	128	6	17	20	22	27	27	25
	1k	128	6	17	19	22	27	27	25

^aAbbreviations: Res, reserpine; Om, omeprazole; Nor, norfloxacin; Cip, ciprofloxacin; Ofx, ofloxacin; Lvx, levofloxacin; Spx, sparfloxacin; Mxf, moxifloxacin; C, chloramphenicol.