Table 1.
Main characteristics of patients and treatment.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | |
| Patient | Male, 12 y.o. | Female, 8 y.o. | Female, 13 y.o. | Female, 8 y.o. |
| Diagnosis | Ewing Sarcoma extraosseous, intrathoracic | Rhabdomyosarcoma mediastinum, stage III | Rhabdomyosarcoma anus. Metastasis lymphnodes intrapelvic, inguinal and osseous |
Wilm's tumour of the left kidney. (Multiple lung metastasis). Multiple liver metastasis |
| Status | After chemotherapy + surgery + chemotherapy | After chemotherapy | After chemotherapy | After chemotherapy + left nefrectomy + chemo-radiotherapy for lung metastasis |
| Radiotherapy dose prescription | Total = 54.4 Gy, | Total = 50.4 Gy, | Total = 50.4 Gy, | Total = 18 Gy, |
| 1.6 Gy/fraction | 1.8 Gy/fraction | 1.8 Gy/fraction | 1.2 Gy/fraction | |
| 2 fractions/day | 1 fraction/day | 1 fraction/day | 1 fraction/day | |
| I course (PTV1) = 44.8 Gy | I course (PTV1) = 45 Gy | I course (PTV1) = 45 Gy | ||
| II course(PTV2) = 9.6 Gy (boost, excludes surgical scar) | II course (PTV2) = 5.4 Gy (boost) | II course (PTV2) = 5.4 Gy (boost, excludes the two inguinal nodes regions) | ||
| Target volumes | PTV1 = 564 cm3 | PTV1 = 109 cm3 | PTV1 = 618 cm3 | PTV1 = 1234 cm3 |
| PTV2 = 549 cm3 | PTV2 = 72 cm3 | PTV2 = 193 cm3 | ||
| Organs at risk dose objectives | Lung1 < 15 Gy | Lung1 < 15 Gy | Rectum1 < 40 Gy | Kidney1 < 10 Gy |
| Heart1 < 30 Gy | Heart1 < 30 Gy | Bladder1 < 30 Gy | ||
| Vertebra1 < 20 Gy | Vertebra1 < 20 Gy | Uterus1 < 20 Gy | ||
| Spinal cord2 < 45 Gy | Spinal cord2 < 45 Gy | Femural heads1 < 20 Gy | ||
| Beam arrangement | 6 fields. (both courses) Gantry angles: 180, 165, 125, 90, 60, 340 |
7 fields. (both courses) Gantry angles: 0, 30, 100, 130, 230, 260, 330 |
I course: 7 fields. Gantry angles: 0, 51, 103, 154, 206, 257, 308 |
5 fields Gantry angles: 0, 72, 144, 216, 288 |
| II course: 5 fields: Gantry angles: 0, 72, 125, 235, 288 |
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1: mean dose; 2: maximum dose