Figure 4.
Stabilization of Nintra by the mutant DTS5 proteasome subunit. Time-course analysis of Nintra accumulation in ptc-gal4 hs-Nintra/+; UAS-DTS5/+ wing imaginal discs. Fifteen minutes after heat induction, Nintra was detected in all imaginal disc cells (A), and gradually disappeared in cells outside the domain of expression of ptc-gal4 (B) 1 hr after heat shock. Twelve hours after heat shock, Nintra was detected only in cells in the ptc-DT5-expressing cells (C).