Figure 1.

PLZF genomic DNA sequence map shows coverage of BAC (BWXD 109) by λ clones (B), phage clones (L), and a cosmid clone (C). Sequenced ends are indicated by open (T3 end) or closed (T7 end) triangles. Selected subclones completely sequenced are shown as solid lines while clones with only ends sequenced are shown as dashed lines. Shaded vertical bars represent overlapping segments between subclones. “B gap 1–5” are not covered by the λ clones but are closed by amplification of BAC DNA. Exons are shown as black boxes, and arrows indicate the breakpoints identified in six patients previously described (7).