Table 1.
Cardiovascular parameters of Vav2−/− mice
| Parameter | Vav2+/+ | Vav2−/− |
|---|---|---|
| Systolic arterial pressure (mm Hg) | ||
| Unconscious state | 81.8 ± 1.7 | 108.2 ± 3.1* |
| Conscious state | 116.0 ± 6.0 | 138.0 ± 4.1* |
| Diastolic arterial pressure (mm Hg) | 54.0 ± 1.9 | 65.5 ± 2.1* |
| Mean arterial pressure (mm Hg) | 63.2 ± 1.7 | 79.7 ± 2.2* |
| Heart rate (beats/min) | ||
| Unconscious state | 328 ± 17 | 450 ± 27* |
| Conscious state | 520 ± 36 | 701 ± 87* |
Values represent the SEM and SD of the experimental data obtained. Asterisks indicate p < 0.01. n = 10 (for awake mice), 17 (for anesthetized Vav2+/+ mice), and 19 (for anesthetized Vav2−/− mice).