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. 2007 Feb 6;6:5. doi: 10.1186/1476-069X-6-5

Table 2.

Crude and Adjusted Odds Ratios and 95% CIs for Skin Lesions Predicted by GST Polymorphisms.

Drinking Water Arsenic Concentrations

Crude Model 1 Adjusted Model 1
Genotype OR (95% CI) p-value OR (95% CI) p-value
GSTP1
AA 1.0 1.0
AG 0.90 (0.69–1.17) 0.44 0.89 (0.68–1.17) 0.41
GG 1.79 (1.12–2.88) 0.02 1.86 (1.15–3.00) 0.01
GSTT1 null 1.0 1.0
GSTT1 wildtype 1.52 (1.08–2.13) 0.02 1.56 (1.10–2.19) 0.01
GSTM1 null 1.0 1.0
GSTM1 wildtype 1.0 (0.78–1.29) 0.98 0.99 (0.77–1.28) 0.95

Crude Models adjusted for As concentration of well or As concentration of well water. Model 1 adjusted for L/day of water, well As concentration, age, gender, education, BMI, chewing tobacco, betel nut use, and smoking status