Table 2.
Crude and Adjusted Odds Ratios and 95% CIs for Skin Lesions Predicted by GST Polymorphisms.
| Drinking Water Arsenic Concentrations | ||||
| Crude Model 1 | Adjusted Model 1 | |||
| Genotype | OR (95% CI) | p-value | OR (95% CI) | p-value |
| GSTP1 | ||||
| AA | 1.0 | 1.0 | ||
| AG | 0.90 (0.69–1.17) | 0.44 | 0.89 (0.68–1.17) | 0.41 |
| GG | 1.79 (1.12–2.88) | 0.02 | 1.86 (1.15–3.00) | 0.01 |
| GSTT1 null | 1.0 | 1.0 | ||
| GSTT1 wildtype | 1.52 (1.08–2.13) | 0.02 | 1.56 (1.10–2.19) | 0.01 |
| GSTM1 null | 1.0 | 1.0 | ||
| GSTM1 wildtype | 1.0 (0.78–1.29) | 0.98 | 0.99 (0.77–1.28) | 0.95 |
Crude Models adjusted for As concentration of well or As concentration of well water. Model 1 adjusted for L/day of water, well As concentration, age, gender, education, BMI, chewing tobacco, betel nut use, and smoking status