Abstract
A 7-day course of either cephradine or amoxicillin-clavulanate treatment caused no significant change in fecal flora composition, except that staphylococci were virtually eliminated in both groups. Some amoxicillin-resistant coliforms were isolated after treatment in both groups, but cephradine- or amoxicillin-clavulanate-resistant coliforms were rarely isolated.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brumfitt W., Franklin I., Grady D., Hamilton-Miller J. M., Iliffe A. Changes in the pharmacokinetics of ciprofloxacin and fecal flora during administration of a 7-day course to human volunteers. Antimicrob Agents Chemother. 1984 Nov;26(5):757–761. doi: 10.1128/aac.26.5.757. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brumfitt W., Hamilton-Miller J. M., Gargan R. A., Cooper J., Smith G. W. Long-term prophylaxis of urinary infections in women: comparative trial of trimethoprim, methenamine hippurate and topical povidone-iodine. J Urol. 1983 Dec;130(6):1110–1114. doi: 10.1016/s0022-5347(17)51709-7. [DOI] [PubMed] [Google Scholar]
- Cooke E. M., Ewins S., Shooter R. A. Changing faecal population of Escherichia coli in hospital medical patients. Br Med J. 1969 Dec 6;4(5683):593–595. doi: 10.1136/bmj.4.5683.593. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gaya H., Adnitt P. I., Turner P. Changes in gut flora after cephalexin treatment. Br Med J. 1970 Sep 12;3(5723):624–625. doi: 10.1136/bmj.3.5723.624. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hartley C. L., Clements H. M., Linton K. B. Effects of cephalexin, erythromycin and clindamycin on the aerobic Gram-negative faecal flora in man. J Med Microbiol. 1978 May;11(2):125–135. doi: 10.1099/00222615-11-2-125. [DOI] [PubMed] [Google Scholar]
- Lacey R. W., Lord V. L., Howson G. L., Luxton D. E., Trotter I. S. Double-blind study to compare the selection of antibiotic resistance by amoxycillin or cephradine in the commensal flora. Lancet. 1983 Sep 3;2(8349):529–532. doi: 10.1016/s0140-6736(83)90566-4. [DOI] [PubMed] [Google Scholar]
- Sutter V. L., Finegold S. M. The effect of antimicrobial agents on human faecal flora: studies with cephalexin, cyclacillin and clindamycin. Soc Appl Bacteriol Symp Ser. 1974;3(0):229–240. [PubMed] [Google Scholar]