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Effect of paclitaxel on cross-sectional area of C-fibres. Graph shows the mean ± SEM of the C-fibre area in vehicle-treated and paclitaxel-treated nerves at days 7, 27 and 160 post-initiation of treatment. At each time point, 120 C-fibres were measured from two vehicle-treated rats and 180 C-fibres from three paclitaxel-treated rats. Vehicle n = 120, paclitaxel n = 180: #p < 0.01, two-tailed unpaired t-tests, Welch correction applied as appropriate.
