Table 1.
Day 7 vehicle | Day 7 paclitaxel | Day 27 vehicle | Day 27 paclitaxel | Day 160 vehicle | Day 160 paclitaxel | |
---|---|---|---|---|---|---|
Cross-sectional nerve area (μm2) | 37,958 ± 3277 | 33,236 ± 2055 | 35,219 ± 3128 | 38,496 ± 2264 | 46,695 ± 4453 | 44,089 ± 2544 |
Density of myelinated axons (no./μm2) | 0.077 ± 0.052 | 0.025 ± 0.001 | 0.022 ± 0.001 | 0.019 ± 0.001 | 0.018 ± 0.001 | 0.018 ± 0.001 |
Density of C-fibres (no./μm2) | 0.099 ± 0.006 | 0.092 ± 0.007 | 0.082 ± 0.006 | 0.074 ± 0.005 | 0.069 ± 0.010 | 0.072 ± 0.006 |
Values expressed as means ± SEM, n = 3 at each time point for nerve areas and myelinated axon density, n = 2 at each time point for C-fibre density.