Fig. 5.
Activated iNKT cells enhance B cell memory. (A) GMTs and 95% C.I. of H3N2-specific antibodies in C57BL/6 WT mice before and after two immunizations (arrows) with H3N2 or H3N2 plus αGC and a subsequent boost (arrowhead) with H3N2 alone. (B) Numbers (average ± SD) of H3N2-IgG ASC precursors per 106 B lymphocytes found on week 30 in the spleens from two groups of mice primed as in A. Results are from one experiment representative of two, in which seven mice per group were analyzed. Asterisks indicate statistically different values (∗, P < 0.05; ∗∗, P < 0.01) between the two groups of mice.