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. 1999 Sep 28;96(20):11458–11463. doi: 10.1073/pnas.96.20.11458

Figure 5.

Figure 5

Neuron survival supported by NNT-1/BSF-3. Chicken embryo motor (A) and sympathetic (B) neurons were exposed in culture for 3 days to a concentration range of NNT-1/BSF-3 or CNTF. The horizontal line in A indicates the survival of motor neurons exposed to NNT-1/BSF-3 buffer as a control. Sympathetic neurons exposed to NNT-1/BSF-3 buffer do not survive and therefore do not generate OD. OD values given by NNT-1/BSF-3 concentrations above 0.1 ng/ml or by CNTF concentrations above 0.01 ng/ml were higher than those given by NNT-1/BSF-3 buffer (n = 5, P < 0.001). The experiment on motor neurons was done three times and the one on sympathetic neurons twice, with similar results.