Table 1.
Cox multivariate analysis demonstrating the independent risk factors for the cancer-specific death of the patients with ovarian cancer (n = 70)
Variable | n | Overall survival, multivariate risk ratio | P value | Progression-free survival, multivariate risk ratio | P value |
---|---|---|---|---|---|
Analysis with PD-L1 expression | |||||
PD-L1 expression | 0.011 | 0.027 | |||
Low | 22 | 1 | 1 | ||
High | 48 | 4.26 (1.39–12.94) | 2.57 (1.11–5.93) | ||
Tumor status | 0.041 | ||||
pT1 + pT2 | 31 | 1 | |||
pT3 | 39 | 4.05 (1.06–15.50) | |||
LN metastasis | 0.027 | 0.002 | |||
pN0 | 56 | 1 | 1 | ||
pN1 | 14 | 2.98 (1.13–7.83) | 3.37 (1.59–7.15) | ||
Residual tumor | <0.001 | <0.001 | |||
Optimal | 49 | 1 | 1 | ||
Suboptimal | 21 | 8.83 (2.74–28.48) | 5.99 (2.92–2.27) | ||
Analysis with intraepithelial CD8+ TIL | |||||
Intraepithelial CD8+ TIL | <0.001 | 0.001 | |||
Negative | 38 | 7.62 (2.76–21.08) | 3.75 (1.74–8.07) | ||
Positive | 32 | 1 | 1 | ||
LN metastasis | 0.040 | 0.001 | |||
pN0 | 56 | 1 | 1 | ||
pN1 | 14 | 2.72 (1.05–7.08) | 3.43 (1.61–7.34) | ||
Residual tumor | 0.006 | <0.001 | |||
Optimal | 49 | 1 | 1 | ||
Suboptimal | 21 | 3.37 (1.42–7.99) | 5.47 (2.69–11.09) |
Numbers in parentheses represent 95% C.I.