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. 2007 Feb 21;104(9):3360–3365. doi: 10.1073/pnas.0611533104

Table 1.

Cox multivariate analysis demonstrating the independent risk factors for the cancer-specific death of the patients with ovarian cancer (n = 70)

Variable n Overall survival, multivariate risk ratio P value Progression-free survival, multivariate risk ratio P value
Analysis with PD-L1 expression
PD-L1 expression 0.011 0.027
    Low 22 1 1
    High 48 4.26 (1.39–12.94) 2.57 (1.11–5.93)
Tumor status 0.041
    pT1 + pT2 31 1
    pT3 39 4.05 (1.06–15.50)
LN metastasis 0.027 0.002
    pN0 56 1 1
    pN1 14 2.98 (1.13–7.83) 3.37 (1.59–7.15)
Residual tumor <0.001 <0.001
    Optimal 49 1 1
    Suboptimal 21 8.83 (2.74–28.48) 5.99 (2.92–2.27)
Analysis with intraepithelial CD8+ TIL
Intraepithelial CD8+ TIL <0.001 0.001
    Negative 38 7.62 (2.76–21.08) 3.75 (1.74–8.07)
    Positive 32 1 1
LN metastasis 0.040 0.001
    pN0 56 1 1
    pN1 14 2.72 (1.05–7.08) 3.43 (1.61–7.34)
Residual tumor 0.006 <0.001
    Optimal 49 1 1
    Suboptimal 21 3.37 (1.42–7.99) 5.47 (2.69–11.09)

Numbers in parentheses represent 95% C.I.