Table 2.

Complementation of cephalosporin sensitivity of the ΔprkC2 mutant in MM9YE supplemented with ribose (0.2%), Em, and rhamnose (1%)

Antibiotic	Median fold sensitization*
	Vector control†	prkC+ complementation‡
Cefuroxime	192	6
Ceftazidime	128	4
Cefotaxime	768	5
Ceftriaxone	128	2

*Paired MIC determinations for the indicated strains were made in five or six independent experiments; the median fold sensitization (calculated as indicated) is reported. Values from the individual experiments are available in SI.

^†Calculated as MIC (wild type + vector)/MIC (ΔprkC2 + vector). Vector was pCJK96.

^‡Calculated as MIC (wild type + vector)/MIC (ΔprkC2 + prkC). Vector was pCJK96, and prkC expression plasmid was pCJK104.