Table 1.
LRP ligands other than tat do not induce high levels of apoptosis after 24 h of treatment
Condition | Neuronal apoptosis, % | Astrocyte apoptosis, % |
---|---|---|
Control | 2.8 ± 1.4 | 1.6 ± 0.4 |
Tat | 61.2 ± 9.7* | 18.7 ± 5.8* |
Lactoferrin | 3.2 ± 0.23 | 1.5 ± 0.6 |
α2macroglobulin | 1.8 ± 0.8 | 1.1 ± 0.7 |
ApoE4 | 7.8 ± 1.7*† | 3.3 ± 0.9*† |
Values represent mean ± SD (n = 5).
*, P < 0.005 compared with control conditions.
†, P < 0.001 compared with tat conditions.