Table 2.
Haplotypes of CXCR1 and CXCR2 sites that are associated with disease progression
| Haplotype | Polymorphisms |
Haplotype distribution |
P value |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CTR |
SP |
RP |
CTR vs. SP vs. RP |
SP vs. RP |
||||||||||||
| 219 | 200 | 300 | 142 | 7222390 | 7222391 | 1913 | 7222360 | Counts | Freq | Counts | Freq | Counts | Freq | Corrected | ||
| CXCR1_HA | C | C | T | C | — | — | — | — | 903/942 | 0.958 | 496/526 | 0.943 | 172/172 | 1.000 | 0.00083 | 0.00029 |
| CXCR1_Ha | T | T | G | T | — | — | — | — | 39/942 | 0.041 | 30/526 | 0.057 | 0/172 | 0.000 | 0.00083 | 0.00029 |
| CXCR2_H1 | — | — | — | — | T | — | C | A | 446/940 | 0.474 | 271/524 | 0.516 | 96/170 | 0.565 | 0.053 | 0.290 |
| CXCR2_H2 | — | — | — | — | T | T | C | A | 445/940 | 0.474 | 217/524 | 0.415 | 73/170 | 0.429 | 0.077 | 0.721 |
| CXCR2_H3 | — | — | — | — | G | — | T | G | 39/940 | 0.041 | 31/524 | 0.059 | 0/170 | 0.000 | 0.00064 | 0.00018 |
| CXCR2_H4 | — | — | — | — | T | — | T | A | 10/940 | 0.010 | 5/524 | 0.009 | 1/170 | 0.006 | 0.923 | 1.000 |
| CXCR1–2_H1 | C | C | T | C | T | — | C | A | 447/938 | 0.474 | 272/522 | 0.517 | 97/172 | 0.564 | 0.054 | 0.334 |
| CXCR1–2_H2 | C | C | T | C | T | T | C | A | 444/938 | 0.472 | 218/522 | 0.415 | 74/172 | 0.430 | 0.096 | 0.790 |
| CXCR1–2_H3 | T | T | G | T | G | — | T | G | 37/938 | 0.039 | 29/522 | 0.055 | 0/172 | 0.000 | 0.00108 | 0.00029 |
| CXCR1–2_H4 | C | C | T | C | T | — | T | A | 10/938 | 0.010 | 3/522 | 0.006 | 1/172 | 0.006 | 0.839 | 1.000 |
Freq, frequency.