. 2005 Dec 8;571(Pt 1):221–230. doi: 10.1113/jphysiol.2005.100313

Table 1.

Body weight, absolute and relative food intake and serum leptin concentration in male and female pups

	CC	RR	CR	RC
A. Body weight
Male (21 d; g)	46.0 ± 2.73a	29.1 ± 2.09b	31.0 ± 1.30b	48.4 ± 1.30a
Female (21 d; g)	38.7 ± 1.93a^*	22.9 ± 0.69b^*	27.3 ± 0.36b^*	42.9 ± 1.04a^*
B. Serum leptin concentration in males
Leptin (ng ml⁻¹)	4.7 ± 0.83a	2.3 ± 0.26a^*	5.2 ± 0.60a^*	9.3 ± 1.56b^*
Body weight (g)	513.2 ± 10.5a^*	417.7 ± 10.8b^*	458.7 ± 17.2b^*	531.1 ± 8.6a^*
Food intake (g)	33.8 ± 1.77a^*	29.8 ± 1.03a,b^*	26.6 ± 0.76b^*	32.6 ± 0.49a^*
Food intake (g (g body wt)⁻¹)	0.066 ± 0.003a,b	0.072 ± 0.004a	0.058 ± 0.001b^*	0.061 ± 0.002a,b
C. Serum leptin concentration in females
Leptin (ng ml⁻¹)	3.4 ± 0.46a	1.4 ± 0.21b^*	1.8 ± 0.30b,c^*	2.3 ± 0.28a,c^*
Body weight (g)	326.1 ± 10.9a^*	252.4 ± 16.4b^*	262.9 ± 10.6b,c^*	317.7 ± 17.5a,c^*
Food intake (g)	22.8 ± 1.03a^*	19.5 ± 0.19b^*	19.5 ± 0.40b^*	20.1 ± 2.20a,b^*
Food intake (g (g body wt)⁻¹)	0.070 ± 0.003a,b	0.079 ± 0.004a	0.075 ± 0.003a^*	0.063 ± 0.002b

A, male and female pup body weight at 21 days of age. Maternal groups: mothers fed with control (C, 20% casein) or restricted (R, 10% casein) diet during pregnancy (first letter) and lactation (second letter). n = 5–6 litters. B, male offspring serum leptin at 110 days, body weight and absolute and relative food intake at 100 days of age. From 5 CC litters, 5 RR litters, 5 CR litters, and 4 RC litters. C, female offspring serum leptin at 110 days, body weight and absolute and relative food intake at 100 days of age. From 5 CC litters, 5 RR litters, 6 CR litters, and 6 RC litters. Groups not sharing a letter are statistically different

Female versus male P≤ 0.05. All values are mean ±s.e.m.