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Differences in DSB formation between sir2 and wild-type strains (ΔR) as a function of distance from the telomere. For this analysis, we averaged ΔR in bins of 10 kb for all elements on the microarray for all chromosomes. Standard error bars are shown. The elevation of DSB formation within ≈10 kb of the chromosome end is evident, as is the suppression of DSBs that extends to ≈120 kb from the telomere.
