. Author manuscript; available in PMC: 2007 Mar 1.

Published in final edited form as: J Mol Biol. 2006 Nov 3;366(1):53–66. doi: 10.1016/j.jmb.2006.10.09

TABLE 6.

Apparent K_d values^* for MSH2-MSH3, msh2Δ1-MSH3, and MSH2-msh3K187A, K189A binding to DNA substrates

	homoduplex substrate	+1 substrate	+8 substrate
MSH2-MSH3^**	220 nM +/− 26	110 nM +/− 5	50 nM +/− 6
msh2Δ1-MSH3	> 300 nM	> 300 nM	168 nM +/− 33
MSH2-msh3K187A,K189A	131 nM +/− 10	126 nM +/− 3	86 nM +/− 15

The values represent the protein concentration at 50% maximal binding for each substrate and are an average of at least 3 independent experiments (± SEM).

^**

Data from Surtees and Alani.¹⁰