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. 1986 Sep;30(3):505–507. doi: 10.1128/aac.30.3.505

Aztreonam concentrations in human tissues obtained during thoracic and gynecologic surgery.

T R Beam Jr, R P Galask, L T Friedhoff, T B Platt, M A Leitz
PMCID: PMC180589  PMID: 3777914

Abstract

The concentrations of aztreonam in human tissues obtained during surgery were measured after a single 2-g intravenous dose. The average concentration in the skeletal muscle, atrial appendage, lung, sternum, pericardial fluid, endometrium, myometrium, fallopian tube, and ovary varied from 3 to 33 micrograms/g (or microgram/ml). These concentrations significantly exceed the MIC for 90% of strains for most members of the family Enterobacteriaceae.

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Selected References

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