Figure 7.

Systemic administration of BQ788 inhibits melanoma tumor growth in nude mice. The experiments were similar to those described in Fig. 6, except that the drug and vehicle were injected daily i.p. In A, the data for the six BQ788-treated mice were pooled. In B, separate curves are drawn for the data from the three mice in which BQ788 slowed tumor growth and for the data from the three mice in which BQ788 caused the tumors to regress. P values were calculated by using the Student’s t test and are indicated by ∗ when significantly different from controls (P < 0.05).