Table 1.

Treatment with BQ788 increases TUNEL staining in certain melanoma cell lines in culture

Cell line	BQ788	Control	Δx
RPMI 7951	76.4 ± 6.1	1.9 ± 1.1	40.2*
SK MEL 28	7.4 ± 1.6	0.4 ± 0.3	18.5*
A375	21.6 ± 5.4	1.6 ± 0.1	13.5*
SK MEL 5	1.5 ± 1.3	0.5 ± 0.2	3
SK MEL 24	1.2 ± 0.5	0.6 ± 0.2	2
SK MEL 31	7.8 ± 1.6	3.5 ± 1.2	2.2
SK MEL 3	1.4 ± 0.4	1.7 ± 1.1	0.8
Kidney 293	2.8 ± 1.3	3.4 ± 0.2	0.8

TUNEL staining is expressed as percent positive cells after 4 days in culture in the presence of 100 μM BQ788 and compared with vehicle-treated cells as the control. Δx represents the fold increase; *P < 0.05. P for percent values was calculated by using the Mann–Whitney test (n = 3–5).