Table 1.
Ligand | rhIL-18
|
rmIL-18
|
||||
---|---|---|---|---|---|---|
KOn, 104/Ms | KOff, 10−4/s | Kd, nM | KOn, 105/Ms | KOff, 10−4/s | Kd, nM | |
hIL-18BP | 7.23 ± 0.08 | 0.31 ± 0.09 | 0.4 ± 0.1 | 2.0 ± 0.3 | 0.19 ± 0.08 | 0.09 ± 0.03 |
MC54L | 9.7 ± 0.2 | 10 ± 1 | 10 ± 1 | 2.9 ± 0.6 | 20 ± 2 | 7.2 ± 0.9 |
MC53L | 7 ± 1 | 1.5 ± 0.4 | 2.1 ± 0.7 | 4.2 ± 0.2 | 0.4 ± 0.3 | 0.9 ± 0.7 |