Table 1.
Virulence properties of a S. typhimurium Dam− mutant in BALB/c mice
Bacterial strain | LD50 (oral)* | LD50 (i.p.) |
---|---|---|
SL1344 (wild type) | 6 × 104 | <10 |
SV1610 (Dam−) | >8.8 × 108 | 6.5 × 104 |
SV1610/pTP166 | 2.75 × 105 | <35 |
SV4036 (MutL−) | 2.4 × 106 | <17 |
Oral inoculation was done by suspending bacteria in bicarbonate buffer before administration to mice.