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αCTDI alone is insufficient to mediate large-scale DNA compaction. (A–C) Contour length distributions of DNA in the absence (hatched bars; top) and presence (grey bars; bottom) of RNAP, from experiments with ΔαCTDII RNAP derivatives. Apparent DNA compaction is presented as mean±s.e.m. Because of the paucity and scatter of the data, the mean value in (C) represents the arithmetical average of the data. αCTD, α-subunit carboxy-terminal domain; RNAP, RNA polymerase.
