. Author manuscript; available in PMC: 2007 Mar 2.

Published in final edited form as: Eur J Nucl Med Mol Imaging. 2007 Feb;34(2):237–246. doi: 10.1007/s00259-006-0222-3

Table 4.

Comparison of tumor to tissue ratios between conventional targeting and pretargeting

Organ	Conventional ^a	Pretargeting ^b
Blood	3.8 ± 1.4	3.0 ± 0.7
Liver	0.5 ± 0.2	5.1 ± 0.7
Heart	8.7 ± 2.9	14 ± 6
Lung	4.7 ± 1.2	7.8 ± 2.1
Spleen	1.2 ± 0.4	10 ± 2
Muscle	18 ± 5	25 ± 4
Kidney	0.7 ± 0.3	1.0 ± 0.2

. Calculated from the biodistribution data at 2 d in mice receiving 30 μg ¹¹¹In-MN14 (10). Tumor size: 1.00 ± 0.25 g. (N = 4).

. Calculated from the biodistribution data in mice selected for similar tumor size (1.01 ± 0.12 g) (Mouse No. 10, 12, 16 and 20 in Table 2) also receiving 30 μg MORF-MN14 and also a 2 d pretargeting interval.