A, CK myocardial pseudo first-order rate constant (Kfor) for healthy subjects (Normal), patients with LVH, and others with LVH with CHF (LVH+CHF). Note that Kfor is not reduced by LVH but only in LVH+CHF. B, Net ATP flux through the CK reaction (CK flux) in healthy subjects (Normal), patients with LVH, and others with LVH with CHF (LVH+CHF).