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. Author manuscript; available in PMC: 2007 Mar 2.
Published in final edited form as: Circulation. 2006 Sep 4;114(11):1151–1158. doi: 10.1161/CIRCULATIONAHA.106.613646

Figure 3.

Figure 3

LVH severity, as indexed by left ventricular mass index (LVMI; A and B) and left ventricular ejection fraction (EF; C and D) versus ATP kinetics, as indexed by Kfor (above) and CK flux (below) for LVH (▲) and LVH+CHF (○). Neither Kfor nor CK flux correlated with the severity of LVH (r2 < 0.03 for both in all 20 patients) or with ejection fraction. It is the presence of CHF, not the severity of LVH, that is associated with reduced ATP synthesis through CK. Reduced CK flux occurs in failing hearts with impaired and preserved ejection fractions.