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Proton/deuteron passage from F0 of ATP synthase in mitochondria. Protons enter the cytoplasmic half-channel and reach Asp61 on subunits c. Protonated Asp61 moves into the lipid bilayer. When protonated Asp61 reaches the matrix half-channel, it is deprotonated by the stator charge of Arg210 on subunit a. A temporary stutter of the rotor is expected during the passage of deuteron. *The ratio of deuterons (D+) to protons (H+) is ~1:15000.
