Table 2.
Demographics and clinical features of patients RT-PCR positive for human metapneumovirus (hMPV)
| Case | Date (month/year) | hMPV isolate, genotype (Peret et al., 2004), GenBank accession number | Race | Gender | Age (year) | Days in hospital | Co-infectiona | Reason for assessment (diagnosis) | Other diagnoses of interest |
|---|---|---|---|---|---|---|---|---|---|
| 1 | March 2002 | – | Caucasian | F | 54.7 | 14 | – | Obstructive bronchitis without exacerbation | Heart replaced by transplant |
| 2 | March 2002 | IA3-2002, A1, DQ312444 | Caucasian | M | 0.6 | 8 | – | Congestive heart failure, unspecified | Congenital mitral insufficiency |
| 3 | March 2002 | – | Asian | F | 4.6 | 3 | – | Bronchitis, not specified as acute or chronic | |
| 4 | March 2002 | – | Caucasian | F | 8.9 | 2 | – | Pneumonia, organism unspecified | Congenital cytomegalovirus infection |
| 5 | December 2002 | IA4-2002, B1, DQ312445 | Caucasian | F | 6.3 | 3 | – | Fever | Acute lymphoid leukemia in remission; anemia, unspecified |
| 6 | December 2002 | IA5-2002, B1, DQ312446 | Caucasian | F | 5.8 | – | – | Osteopetrosis | Bone marrow transplant |
| 7 | January 2003 | – | Caucasian | F | 78.5 | 10 | – | Obstructive bronchitis with (acute) exacerbation | Respiratory failure |
| 8 | January 2003 | IA6-2003, B1, DQ312447 | Caucasian | F | 9.5 | – | – | Chronic myeloid leukemia without mention of remission | |
| 9 | January 2003 | – | Caucasian | M | 2.7 | 2 | – | Upper respiratory infection (acute), unspecified site | Chronic respiratory disease arising in the perinatal period |
| 10 | January 2003 | IA7-2003, B1, DQ312448 | Caucasian | M | 17.8 | 9 | – | Respiratory failure | Congenital quadriplegic |
| 11 | January 2003 | – | Caucasian | M | 3.5 | 6 | – | Respiratory failure | Chronic respiratory disease arising in the perinatal period; dependence on respirator; pulmonary collapse, other chronic pulmonary heart disease |
| 12 | January 2003 | – | African American | M | 0.8 | 1 | – | Acute bronchiolitis due to other infectious organisms | Pulmonary collapse, congenital anomaly of lung unspecified |
| 13 | January 2003 | IA8-2003, A2, DQ312449 | African American | F | 2.7 | 3 | – | Pneumonia, organism unspecified | Prader–Willi syndrome |
| 14 | January 2003 | IA9-2003, B1, DQ312450 | Caucasian | F | 5.4 | 5 | – | Bacteremia (micrococcus species) | Acute lymphoid leukemia without remission, agranulocytosis |
| 15 | January 2003 | IA10-2003, A1, DQ312451 | Caucasian | F | 22.8 | 8 | – | Respiratory failure | Acute renal failure; systemic lupus erythematosus; nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere |
| 16 | January 2003 | IA11-2003, B1, DQ312452 | Caucasian | F | 18.6 | – | – | Influenza with other respiratory manifestations | |
| 17 | January 2003 | – | Caucasian | F | 0.8 | 11 | – | Respiratory failure | Pneumonia, organism unspecified; agenesis of lung |
| 18 | February 2003 | IA13-2003, B1, DQ312454 | Unknown | F | 0.9 | – | – | Cough | |
| 19 | February 2003 | IA14-2003, A2, DQ312455 | Caucasian | M | 57.7 | 18 | – | Pneumonia due to streptococcus goup A | |
| 20b | February 2003 | – | Caucasian | M | 61.4 | – | – | Myeloid leukemia | Pneumonia; aspergillosis |
| 21 | February 2003 | IA15-2003, A1, DQ312456 | Caucasian | F | 0.3 | 20 | – | Acute bronchiolitis due to other infectious organisms | Tetralogy of fallot; infundibular pulmonic stenosis; ostium secundum type atrial septal defect |
| 22 | February 2003 | IA16-2003, B2, DQ312457 | Caucasian | F | 6.3 | 4 | Influenza B | Other specified aplastic anemias | Acute lymphoid leukemia in remission |
| 23 | February 2003 | IA17-2003, A2, DQ312458 | Unknown | F | 45.0 | – | – | Screening for unspecified condition | |
| 24 | February 2003 | IA-18-2003, B1, DQ312459 | Caucasian | M | 3.9 | 8 | – | Unspecified infectious and parasitic diseases | Postinfectious encephalitis; coma |
| 25b | February 2003 | – | Caucasian | M | 68.7 | 14 | – | Malignant neoplasm lower lobe, bronchus or lung | Pneumococcal pneumonia; abscess of lung; respiratory failure |
| 26 | February 2003 | – | Caucasian | M | 0.1 | 6 | – | Acute bronchiolitis due to respiratory syncytial virusc | Pulmonary collapse; respiratory failure |
| 27 | March 2003 | – | Unknown | M | 1.4 | – | RSV | Acute bronchiolitis due to respiratory syncytial virus | Chronic maxillary sinusitis |
| 28 | March 2003 | IA19-2003, B2, DQ312460 | Caucasian | M | 3.9 | 13 | – | Respiratory failure | Hypertrophic obstructive cardiomyopathy; complications of transplanted liver |
| 29 | March 2003 | – | Caucasian | F | 30.6 | 17 | – | Other pulmonary insufficiency, not elsewhere classified | Other shock without mention of trauma; pneumonia, organism unspecified; anoxic brain damage |
| 30 | April 2003 | IA20-2003, B1, DQ312461 | Caucasian | M | 4.3 | 45 | – | Acute lymphoid leukemia without remission | Other specified aplastic anemias; bacteremia; pseudomonas; hyperpotassemia; other pulmonary insufficiency, not elsewhere classified; hypopotassemia; abnormal liver scan |
| 31 | January 2004 | IA21-2003, A2, DQ312462 | Unknown | F | 4.4 | 3 | – | Fever | Acute lymphoid leukemia in remission; other diseases of nasal cavity and sinuses; agranulocytosis; Other nonspecific abnormal serum enzyme levels |
| 32 | February 2004 | IA22-2003, A2, DQ312463 | Unknown | M | 10.2 | 6 | – | Other specified aplastic anemias | Hypopotassemia; Hodgkin's disease, unspecified |
| 33 | March 2004 | IA23-2004, A2, DQ312464 | Hispanic | M | 1.2 | 1 | – | Foreign body in esophagus | Food/vomit pneumonitis; pulmonary insufficiency following trauma and surgery |
| 34 | March 2004 | IA24-2004, B2, DQ312465 | Unknown | F | 2.1 | 8 | – | Epilepsy, grand mal status | Pneumonitis due to inhalation of food or vomitus; periventricular leukomalacia; unspecified otitis media; esophageal reflux |
Diagnoses were recorded using the International Classification of Diseases, Ninth Revision.
a
Another virus detected in the same culture specimen where hMPV was detected.
b
Patient died.
c
Not confirmed by laboratory microbiological tests.