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. 2007 Feb 13;5(3):e52. doi: 10.1371/journal.pbio.0050052

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© 2007 Westmark and Malter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Alignment of the canonical G-quartet motif with the putative G-quartet sequence in human, mouse, and rat APP mRNAs.

(B) Alignment of the G-rich region of the human, mouse, and rat APP genes. The predicted G-quartet sequence is located at position 825–846 of the mouse gene and is highlighted.