Fig 2.

Kynurenine to tryptophan ratios (kyn/trp) in supernatants of monocytic THP-1 cells in the presence or absence of 100 U/ml IFN-γ, 10 ng/ml or 1 µg/ml lipopolysaccharide (LPS) and treated with atorvastatin for 24 h. Columns show mean values (± s.e.m.) of three experiments performed in triplicate. *P < 0·001 (compared with unstimulated cells), #P < 0·001 (compared with stimulated cells without atorvastatin), ##P < 0·05 (compared with stimulated cells without atorvastatin); note logarithmic scale of the ordinate.