Table 2.
Studies investigating the frequency of concomitant autoimmune disorders in vitiligo
| Reference | n | Thyroid Ab (%) | PCA (%) | ANA (%) | Adrenal Ab (%) | ASMA (%) | AMA (%) |
|---|---|---|---|---|---|---|---|
| [3] Cunliffe et al.* (1968) | 56 | 30* (P < 0.05) | 5.7* (P < 0.004) | – | – | – | – |
| [4] Grimes et al. (1983) | 70 | 11.4 (P < 0.05) | 2.9 (n.s.) | 2.9 (n.s.) | – | 2.9 (n.s.) | – |
| [5] Betterle et al. (1985) | 373 | 18.4 (P < 0.05) | 10.4 (P < 0.001) | – | 1.36 (P < 0.05) | – | – |
| [6] Hann et al. (1983) | 226 | 7.1 (P < 0.01) | 3.5 (n.s.) | 12.4(P < 0.01) | – | 25.7 (P < 0.01) | – |
| [7] Schallreuter et al. (1994) | 205 | 20.0 (P < 0.05) | 16.2 | – | 2.7 | – | – |
| [8] Hegedüs et al. (1994) | 35 | 26 (P < 0.05) | – | – | – | – | – |
| This study (2002) | 106 | 21 (P < 0.05) | 13 (n.s.) | 17 (n.s.) | – | 2 (n.s.) | 0 |
*
Cunliff reported thyroid disease and pernicious anaemia. Thyroid Ab, thyroid autoantibodies; PCA, parietal cell antibodies; ANA, anti-nuclear antibodies; Adrenal Ab, adrenal autoantibodies; ASMA, anti-smooth muscle antibodies; AMA, anti-mitochondrial antibodies.