Table 1.
Antibodies associated with systemic autoimmune diseases
| Antibody | Antigen | Disease |
|---|---|---|
| Antinuclear antibody | Nuclear antigens(dsDNA, ssDNA, histone, Sm,RNP, SS-A/Ro, SS-B/La) | SLE |
| Antinuclear antibody | Nuclear antigens(RNP, 70 kDa protein) | MCTD |
| Antinuclear antibody | Nuclear antigens(DNA, PM1, Jo-1) | Polymyositis,Dermatomyositis |
| Antinuclear antibody | Nuclear antigens(SS-A/Ro, SS-B/La) | Sjogren's syndrome |
| Antinuclear antibody | Nuclear antigens(nucleolar DNA, RNP, Scl70) | PSS |
| Rheumatoid factor(RF, anti-Fc) | Fc portion of IgG | RA |
| Antibodies to platelets | Platelet membrane antigens | SLE |
| Antibodies to RBC | Red blood cell antigens | SLE |
SLE: systemic lupus erythematosus, PSS: progressive systemic sclerosis, Sm: Smith antigen. MCTD: mixed connective tissue disease, RA: rheumatoid arthritis, RNP: ribonucleoprotein, SS-A/Ro: Sjogren's syndrome antigen A/Robert antigen, SS-B/La: Sjogren's syndrome antigen B.